Rotary movement of DNA rotors on nanopores. Best row: Uncooked video with the Cy5 channel of every rotor. Center row: corresponding solitary-particle localization results of equally ends with the DNA rotors. The place of the present frame is marked as orange and blue dots, as well as trajectory of the 10 frames right before The present body is proven as good lines.
Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transportation of macromolecules
The subsequent posts are merged in Scholar. Their mixed citations are counted only for the primary short article.
Deposition and atomic power microscopy of personal phthalocyanine polymers among nanofabricated electrodes
Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond clever style and design in 2005. (nl)
Our study ranges within the biophysics of DNA to artificial cells and outside of. You should take a look under with the spectrum of our recent assignments.
‘At the beginning we looked at biological units having a Bodily perspective and acted on the basis in the instruments we realized. It took a few years just before we started off Doing the job a lot more on the large Organic challenges. I then began to contact it nanobiology, a term that did not exist at time.
Nanopores characterize a sublime and functional Resource to evaluate solitary molecules. We investigation novel detection modes with reliable-condition nanopores and also a variety of strategies to measure proteins with nanopores. Assignments encompass the following:
The rotors harness energy from the nanoscale drinking water and ion flow that may be produced by a static chemical or electrochemical prospective gradient from the nanopore, that happen to be set up via a salt gradient or utilized voltage, respectively. These artificial nanoengines self-Manage and function autonomously in physiological disorders, suggesting solutions to constructing Electrical power-transducing motors at nanoscale interfaces.
Bulk-surface coupling identifies the mechanistic connection among Min-protein designs cees dekker in vivo As well as in vitro
Screening pseudotopological and nontopological styles for SMC-pushed DNA loop extrusion towards roadblock-traversal experiments
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2004, discovery of latest physics in translocation of DNA via nanopores; to start with experimental review of ions conduction in nanofluidic channels; very first electrochemistry with individual one-wall carbon nanotubes; STM detection and control of phonons in carbon nanotubes; to start with electrical docking of microtubules on kinesin-coated nanostructures; 1st biophysics characterization from the mechanical Attributes of double-stranded RNA; and very first solitary-molecule study of DNA translocation by a restriction-modification enzyme.